Summary

Name DOCK10
Full Name Dedicator of cytokinesis protein 10
Synonyms Zizimin-3 | KIAA0694, ZIZ3
Primary ID Q96BY6
Links - -
Type protein
Relations 1
Function Guanine nucleotide-exchange factor (GEF) that activates CDC42 and RAC1 by exchanging bound GDP for free GTP. Essential for dendritic spine morphogenesis in Purkinje cells and in hippocampal neurons, via a CDC42-mediated pathway. Sustains B-cell lymphopoiesis in secondary lymphoid tissues and regulates FCER2/CD23 expression.

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Relations

Regulator Mechanism target score ℹ
+ DOCK10up-regulates activity img/direct-activation.png guanine nucleotide exchange factor RAC1 0.495
Publications: 1 Organism: Homo Sapiens