3.0
Summary
| Name |  INTS12
|
| Full Name | Integrator complex subunit 12 |
| Synonyms | Int12, PHD finger protein 22 | PHF22 |
| Primary ID | Q96CB8 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (PubMed:16239144). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | INTS12 | form complex 
binding
|
Integrator complex | 0.741 |
| Publications: | 1 | Organism: | Drosophila Melanogaster | |