4.0
Summary
| Name |  CDCA7L
|
| Full Name | Cell division cycle-associated 7-like protein |
| Synonyms | Protein JPO2, Transcription factor RAM2 | HR1, JPO2, R1 |
| Primary ID | Q96GN5 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1. |
transcriptional regulation