3.0
Summary
| Name |  APIP
|
| Full Name | Methylthioribulose-1-phosphate dehydratase |
| Synonyms | MTRu-1-P dehydratase, APAF1-interacting protein, hAPIP |
| Primary ID | Q96GX9 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death. |
binding