+ |
FYN | up-regulates activity
phosphorylation
|
KIRREL1 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262745 |
Tyr605 |
MKDPTNGyYNVRAHE |
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
18258597 |
Here we have characterized Neph1, another SD component, as a novel substrate of SFK. Fyn interacts with and phosphorylates the cytoplasmic domain of Neph1 in vitro and in intact cells. Both tyrosine 637 and 638 of Neph1 are crucial for Neph1-Grb2 binding. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-262746 |
Tyr606 |
KDPTNGYyNVRAHED |
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
18258597 |
Here we have characterized Neph1, another SD component, as a novel substrate of SFK. Fyn interacts with and phosphorylates the cytoplasmic domain of Neph1 in vitro and in intact cells. Both tyrosine 637 and 638 of Neph1 are crucial for Neph1-Grb2 binding. |
|
Publications: |
2 |
Organism: |
Homo Sapiens |