Summary

Name ZNF462
Full Name Zinc finger protein 462
Synonyms Zinc finger PBX1-interacting protein, ZFPIP | KIAA1803
Primary ID Q96JM2
Links - -
Type protein
Relations 1
Function Zinc finger nuclear factor involved in transcription by regulating chromatin structure and organization (PubMed:20219459, PubMed:21570965). Involved in the pluripotency and differentiation of embryonic stem cells by regulating SOX2, POU5F1/OCT4, and NANOG (PubMed:21570965). By binding PBX1, prevents the heterodimerization of PBX1 and HOXA9 and their binding to DNA (By similarity). Regulates neuronal development and neural cell differentiation (PubMed:21570965).

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png binding PBX1 0.316
Publications: 1 Organism: Chlorocebus Aethiops