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Summary
| Name |  DRC1
|
| Full Name | Dynein regulatory complex protein 1 |
| Synonyms | Coiled-coil domain-containing protein 164 | C2orf39, CCDC164 |
| Primary ID | Q96MC2 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules (PubMed:23354437). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | DRC1 | form complex 
binding
|
Nexin-dynein regulatory complex | |
| Publications: | 1 | Organism: | Homo Sapiens | |