Relation Results
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Summary
Name
TOX2
Full Name
TOX high mobility group box family member 2
Synonyms
Granulosa cell HMG box protein 1, GCX-1 | C20orf100, GCX1
Primary ID
Q96NM4
Links
-
-
Type
protein
Relations
1
Function
Putative transcriptional activator involved in the hypothalamo-pituitary-gonadal system.
Viewer
Type:
All
Direct
Indirect
Up-regulates
Down-regulates
Binding
Transcription
Score:
0.0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
Layout:
Compact
Moderate
Relaxed
SPV
0.295
TOX2
TBX21
Protein
Protein family
Complex
Chemical/Molecule
Phenotype/Stimulus
Nucleus
Membrane
Up-regulates
Down-regulates
Physical interaction
Unknown
Direct
Indirect
Binding
Search Tools
Refine search:
by mechanism
none
transcriptional regulation
by effect
none
up-regulates quantity by expression
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
HEK-293T cell
Relations
Regulator
Mechanism
target
score
ℹ
+
TOX2
up-regulates quantity by expression
transcriptional regulation
TBX21
0.295
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-266097
Homo sapiens
HEK-293T Cell
pmid
sentence
25352127
We subsequently found that TOX2 was independent of ETS-1 but could directly upregulate the transcription of TBX21 (encoding T-BET).
Publications:
1
Organism:
Homo Sapiens
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