3.0
Summary
| Name |  RAB3IPView Modifications |
| Full Name | Rab-3A-interacting protein |
| Synonyms | Rab3A-interacting protein, Rabin-3, SSX2-interacting protein | RABIN8 |
| Primary ID | Q96QF0 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B (PubMed:12221131, PubMed:26824392). Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (PubMed:12221131, PubMed:26824392). Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5 (PubMed:20937701, PubMed:26824392). Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface (PubMed:12221131). Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (PubMed:20890297). |
phosphorylation