3.0
Summary
| Name |  PURB
|
| Full Name | Transcriptional activator protein Pur-beta |
| Synonyms | Purine-rich element-binding protein B | |
| Primary ID | Q96QR8 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity). |
transcriptional regulation