Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-263032 |
Ser514 |
KKHARHFsLDVHPYI |
Mus musculus |
|
pmid |
sentence |
22445341 |
We identified 5 potential NDR1 substrates in the mouse brain and chose two for functional validation. We show that one NDR1 substrate is another kinase, AP-2 associated kinase-1 (AAK1) which regulates dendritic branching as a result of NDR1 phosphorylation. Another substrate is the Rab8 guanine nucleotide exchange factor (GEF) Rabin8 (a Sec2p homolog) which we find is involved in spine synapse formation. |
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