Relation Results

Summary

Name CCNL2
Full Name Cyclin-L2
Synonyms Paneth cell-enhanced expression protein
Primary ID Q96S94
Links - -
Type protein
Relations 3
Function Involved in pre-mRNA splicing. May induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors.

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Type: Score: Layout: SPV 
0.576DYRK1ACCNL2

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▶Modifications Tables

Relations
Regulator
Mechanism
target
score ℹ
+ DYRK1A img/unknown.png phosphorylation CCNL2 0.576
Identifier Residue Sequence Organism Cell Line
SIGNOR-251087 Ser330 LDGTSGFsPAPKLVE Chlorocebus aethiops COS-7 Cell
pmid sentence
DYRK1A interacted with cyclin L2 in pull-down assays, and overexpression of DYRK1A stimulated phosphorylation of cyclin L2 in COS-7 cells. | Three phosphoserines were identified in the slower migrating bands (Fig. 9; Ser-330, Ser-338, and Ser-369). All of these serine residues are located N-terminal of proline residues, consistent with our previous classification of DYRK1A as a “proline-directed” kinase.
Identifier Residue Sequence Organism Cell Line
SIGNOR-251088 Ser338 PAPKLVEsPKEGKGS Chlorocebus aethiops COS-7 Cell
pmid sentence
DYRK1A interacted with cyclin L2 in pull-down assays, and overexpression of DYRK1A stimulated phosphorylation of cyclin L2 in COS-7 cells. | Three phosphoserines were identified in the slower migrating bands (Fig. 9; Ser-330, Ser-338, and Ser-369). All of these serine residues are located N-terminal of proline residues, consistent with our previous classification of DYRK1A as a “proline-directed” kinase.
Identifier Residue Sequence Organism Cell Line
SIGNOR-251089 Ser369 AKKAKADsPVNGLPK Chlorocebus aethiops COS-7 Cell
pmid sentence
DYRK1A interacted with cyclin L2 in pull-down assays, and overexpression of DYRK1A stimulated phosphorylation of cyclin L2 in COS-7 cells. | Three phosphoserines were identified in the slower migrating bands (Fig. 9; Ser-330, Ser-338, and Ser-369). All of these serine residues are located N-terminal of proline residues, consistent with our previous classification of DYRK1A as a “proline-directed” kinase.
Publications: 3 Organism: Chlorocebus Aethiops
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