4.0
Summary
| Name |  OSBPL9
|
| Full Name | Oxysterol-binding protein-related protein 9 |
| Synonyms | ORP-9, OSBP-related protein 9 | ORP9, OSBP4 |
| Primary ID | Q96SU4 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Interacts with OSBPL11 to function as lipid transfer proteins (PubMed:39106189). Together they form a heterodimer that localizes at the ER-trans-Golgi membrane contact sites, and exchanges phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) for phosphatidylinositol-4-phosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate), PI(4)P) between the two organelles, a step that is critical for sphingomyelin synthesis in the Golgi complex (PubMed:39106189). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | OSBPL9 | form complex 
binding
|
OSBPL9-OSBPL11 oxysterol-binding protein-related complex | 0.272 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | OSBPL9 | form complex
binding
|
OSBPL9-OSBPL10 oxysterol-binding protein-related complex | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |