4.0
Summary
| Name |  RBM15
|
| Full Name | RNA-binding protein 15 |
| Synonyms | One-twenty two protein 1, RNA-binding motif protein 15 | OTT, OTT1 |
| Primary ID | Q96T37 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | RNA-binding protein that acts as a key regulator of N6-methyladenosine (m6A) methylation of RNAs, thereby regulating different processes, such as hematopoietic cell homeostasis, alternative splicing of mRNAs and X chromosome inactivation mediated by Xist RNA (PubMed:27602518). Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (By similarity). Plays a key role in m6A methylation, possibly by binding target RNAs and recruiting the WMM complex (PubMed:27602518). Involved in random X inactivation mediated by Xist RNA |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | RBM15 | up-regulates 
binding
|
SON | 0.24 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CNOT4 | down-regulates quantity by destabilization 
ubiquitination
|
RBM15 | 0.359 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RBM15 | form complex 
binding
|
RBM15/NXF1 | 0.489 |
| Publications: | 1 | Organism: | Homo Sapiens | |