Name
|
PHOX2B
|
Full Name |
Paired mesoderm homeobox protein 2B |
Synonyms |
Neuroblastoma Phox, NBPhox, PHOX2B homeodomain protein, Paired-like homeobox 2B | PMX2B |
Primary ID |
Q99453 |
Links |
- - |
Type |
protein |
Relations |
1 |
Function |
Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element. |