Summary

Name NPAS1
Full Name Neuronal PAS domain-containing protein 1
Synonyms Neuronal PAS1, Basic-helix-loop-helix-PAS protein MOP5, Class E basic helix-loop-helix protein 11, bHLHe11, Member of PAS protein 5, PAS domain-containing protein 5 | BHLHE11, MOP5, PASD5
Primary ID Q99742
Links - -
Type protein
Relations 1
Function May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level (By similarity). Forms a heterodimer that binds core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) leading to transcriptional repression on its target gene TH (By similarity).

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Relations

Regulator Mechanism target score
+ down-regulates quantity by repression img/direct_inhibition.png transcriptional regulation TH 0.257
Publications: 1 Organism: Mus Musculus