| + |
FGR |
phosphorylation
|
ACO2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262869 |
Tyr544 |
FDPGQDTyQHPPKDS |
in vitro |
|
| pmid |
sentence |
| 17997986 |
Here, we provide evidence that the flavoprotein of succinate dehydrogenase and aconitase are "in vitro" substrates of Fgr tyrosine kinase. Fgr phosphorylates flavoprotein of succinate dehydrogenase at Y535 and Y596 and aconitase at Y71, Y544 and Y665. Further experiments will be necessary to verify if Fgr is the tyrosine kinase responsible for the tyrosine phosphorylation of these proteins in vivo and to elucidate the role of these phosphorylations. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262870 |
Tyr665 |
VVIGDENyGEGSSRE |
in vitro |
|
| pmid |
sentence |
| 17997986 |
Here, we provide evidence that the flavoprotein of succinate dehydrogenase and aconitase are "in vitro" substrates of Fgr tyrosine kinase. Fgr phosphorylates flavoprotein of succinate dehydrogenase at Y535 and Y596 and aconitase at Y71, Y544 and Y665. Further experiments will be necessary to verify if Fgr is the tyrosine kinase responsible for the tyrosine phosphorylation of these proteins in vivo and to elucidate the role of these phosphorylations. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-262871 |
Tyr71 |
TLSEKIVyGHLDDPA |
in vitro |
|
| pmid |
sentence |
| 17997986 |
Here, we provide evidence that the flavoprotein of succinate dehydrogenase and aconitase are "in vitro" substrates of Fgr tyrosine kinase. Fgr phosphorylates flavoprotein of succinate dehydrogenase at Y535 and Y596 and aconitase at Y71, Y544 and Y665. Further experiments will be necessary to verify if Fgr is the tyrosine kinase responsible for the tyrosine phosphorylation of these proteins in vivo and to elucidate the role of these phosphorylations. |
|
| Publications: |
3 |
Organism: |
In Vitro |
| + |
ACO2 | down-regulates quantity 
chemical modification
|
citrate(3-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266244 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24068518 |
Citrate is converted to cis-aconitate. This is catalyzed by aconitase. Cis-aconitate is an intermediate and is further converted to isocitrate by aconitase. Aconitase is involved in both reactions. In which first dehydration and then rehydration occur and as a result final product isocitrate is obtained. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Citric acid cycle |
| + |
ACO2 | up-regulates quantity 
chemical modification
|
D-threo-isocitrate(3-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266246 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24068518 |
Citrate is converted to cis-aconitate. This is catalyzed by aconitase. Cis-aconitate is an intermediate and is further converted to isocitrate by aconitase. Aconitase is involved in both reactions. In which first dehydration and then rehydration occur and as a result final product isocitrate is obtained. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Citric acid cycle |
3.0
ACO2
- 
- 