Relation Results

Summary

Name SLC29A1
Full Name Equilibrative nucleoside transporter 1
Synonyms Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter, Equilibrative NBMPR-sensitive nucleoside transporter, Nucleoside transporter, es-type, Solute carrier family 29 member 1 | ENT1
Primary ID Q99808
Links - -
Type protein
Relations 2
Function Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhi ...
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Type: Score: Layout: SPV 
0.20.2CSNK2A1SLC29A1PRKCD

Modifications Tables

Relations

Regulator
Mechanism
target
score
+ up-regulates activity img/direct-activation.png phosphorylation SLC29A1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-276063 Ser254 ETKLDLIsKGEEPRA in vitro
pmid sentence
These data suggest that inhibition of CK2-mediated phosphorylation at Ser254 had the same effect on transporter function as the actual loss of Ser254 in mENT1a, implying that this site is constitutively phosphorylated by CK2. 
Publications: 1 Organism: In Vitro
+ up-regulates activity img/direct-activation.png phosphorylation SLC29A1 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-260888 Ser281 QPTNESHsIKAILKN Homo sapiens
pmid sentence
Phosphorylation of hENT1 by PKC has effects on both the function and subcellular trafficking of hENT1
Publications: 1 Organism: Homo Sapiens
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