| Name
|
 TCF25
|
| Full Name |
Ribosome quality control complex subunit TCF25 |
| Synonyms |
Nuclear localized protein 1, Transcription factor 25, TCF-25 | KIAA1049, NULP1 |
| Primary ID |
Q9BQ70 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
1 |
| Function |
Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:30244831). In the RQC complex, required to promote formation of 'Lys-48'-linked polyubiquitin chains during ubiquitination of incompletely synthesized proteins by LTN1 (PubMed:30244831). Also acts as a transcriptional repressor: represses transcription of SRF in vitro and so may play a role in heart development (PubMed:16574069). May play a role in cell death control (By similarity). |
4.0
binding