| + |
VCP | form complex 
binding
|
RQC complex |
0.593 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-277695 |
|
|
|
|
| pmid |
sentence |
| 28528489 |
The ribosome-bound quality control (RQC) complex is a multi-protein complex conserved throughout eukaryotes and composed of the E3 ubiquitin ligase Ltn1/Listerin, the ATPase Cdc48/p97 with its co-factors Ufd1/UFD1L and Npl4/NPLOC4, as well as the factors Rqc1/TCF25 and Rqc2/NEMF (Fig. 1). |
|
| Publications: |
1 |
| + |
UFD1 | form complex
binding
|
RQC complex |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-277696 |
|
|
|
|
| pmid |
sentence |
| 28528489 |
The ribosome-bound quality control (RQC) complex is a multi-protein complex conserved throughout eukaryotes and composed of the E3 ubiquitin ligase Ltn1/Listerin, the ATPase Cdc48/p97 with its co-factors Ufd1/UFD1L and Npl4/NPLOC4, as well as the factors Rqc1/TCF25 and Rqc2/NEMF (Fig. 1). |
|
| Publications: |
1 |
| + |
RQC complex | down-regulates quantity by destabilization 
ubiquitination
|
60S cytosolic large ribosomal subunit |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-277699 |
|
|
|
|
| pmid |
sentence |
| 30940912 |
The stalling of ribosomes during protein synthesis results in the production of truncated polypeptides that can have deleterious effects on cells, and therefore must be eliminated. In eukaryotes, this function is carried out by a dedicated surveillance mechanism known as ribosome-associated protein quality control (RQC). |
|
| Publications: |
1 |
| + |
NPLOC4 | form complex
binding
|
RQC complex |
0.543 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-277697 |
|
|
|
|
| pmid |
sentence |
| 28528489 |
The ribosome-bound quality control (RQC) complex is a multi-protein complex conserved throughout eukaryotes and composed of the E3 ubiquitin ligase Ltn1/Listerin, the ATPase Cdc48/p97 with its co-factors Ufd1/UFD1L and Npl4/NPLOC4, as well as the factors Rqc1/TCF25 and Rqc2/NEMF (Fig. 1). |
|
| Publications: |
1 |
| + |
TCF25 | form complex
binding
|
RQC complex |
0.471 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-277698 |
|
|
|
|
| pmid |
sentence |
| 28528489 |
The ribosome-bound quality control (RQC) complex is a multi-protein complex conserved throughout eukaryotes and composed of the E3 ubiquitin ligase Ltn1/Listerin, the ATPase Cdc48/p97 with its co-factors Ufd1/UFD1L and Npl4/NPLOC4, as well as the factors Rqc1/TCF25 and Rqc2/NEMF (Fig. 1). |
|
| Publications: |
1 |
| + |
LTN1 | form complex
binding
|
RQC complex |
0.508 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-277694 |
|
|
|
|
| pmid |
sentence |
| 28528489 |
The ribosome-bound quality control (RQC) complex is a multi-protein complex conserved throughout eukaryotes and composed of the E3 ubiquitin ligase Ltn1/Listerin, the ATPase Cdc48/p97 with its co-factors Ufd1/UFD1L and Npl4/NPLOC4, as well as the factors Rqc1/TCF25 and Rqc2/NEMF (Fig. 1). |
|
| Publications: |
1 |
| + |
NEMF | form complex
binding
|
RQC complex |
0.528 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-277693 |
|
|
|
|
| pmid |
sentence |
| 28528489 |
The ribosome-bound quality control (RQC) complex is a multi-protein complex conserved throughout eukaryotes and composed of the E3 ubiquitin ligase Ltn1/Listerin, the ATPase Cdc48/p97 with its co-factors Ufd1/UFD1L and Npl4/NPLOC4, as well as the factors Rqc1/TCF25 and Rqc2/NEMF (Fig. 1). |
|
| Publications: |
1 |
3.0
RQC complex
CPX-2656