Summary

Name ECSIT
Full Name Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
Synonyms Protein SITPEC |
Primary ID Q9BQ95
Links - -
Type protein
Relations 3
Function Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity).

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png ubiquitination ECSIT 0.783
Publications: 1 Organism: Mus Musculus
+ up-regulates activity img/direct-activation.png binding MAVS 0.439
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding ECSIT 0.534
Publications: 1 Organism: Homo Sapiens