4.0
Summary
| Name |  MYBBP1AView Modifications |
| Full Name | Myb-binding protein 1A |
| Synonyms | MBB1A_HUMAN | P160 |
| Primary ID | Q9BQG0 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | May activate or repress transcription via interactions with sequence specific DNA-binding proteins (By similarity). Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (By similarity). Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (By similarity). Has a role in rRNA biogenesis together with PWP1 (PubMed:29065309). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | AURKB |
phosphorylation
|
MYBBP1A | 0.391 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | MYBBP1A | form complex 
binding
|
B-WICH complex | 0.484 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | MN1 | up-regulates activity 
binding
|
MYBBP1A | 0.2 |
| Publications: | 1 | Organism: | In Vitro | |