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Summary
Name
DIDO1
Full Name
Death-inducer obliterator 1
Synonyms
DIO-1, hDido1, Death-associated transcription factor 1, DATF-1 | C20orf158, DATF1, KIAA0333
Primary ID
Q9BTC0
Links
-
-
Type
protein
Relations
1
Function
Putative transcription factor, weakly pro-apoptotic when overexpressed (By similarity). Tumor suppressor. Required for early embryonic stem cell development.
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by mechanism
none
transcriptional regulation
by effect
none
up-regulates quantity by expression
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
Mel Ju cell
Relations
Regulator
Mechanism
target
score
ℹ
+
DIDO1
up-regulates quantity by expression
transcriptional regulation
ITGA5
0.2
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-261580
Homo sapiens
Mel Ju Cell
pmid
sentence
22469980
Dido1 upregulates the expression of Integrin αV, thereby influencing the attachment, apoptosis and migration of melanoma cells.
Publications:
1
Organism:
Homo Sapiens