Summary

Name MED18
Full Name Mediator of RNA polymerase II transcription subunit 18
Synonyms Mediator complex subunit 18, p28b |
Primary ID Q9BUE0
Links - -
Type protein
Relations 1
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding Core mediator complex 0.876
Publications: 1 Organism: Homo Sapiens