Summary

Name WDR18
Full Name WD repeat-containing protein 18
Synonyms WDR18_HUMAN |
Primary ID Q9BV38
Links - -
Type protein
Relations 1
Function Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859). Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (PubMed:21326211). May play a role during development (By similarity).

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Relations

Regulator Mechanism target score ℹ
+ WDR18form complex img/form-complex.png binding Rix1 complex 0.863
Publications: 1 Organism: Homo Sapiens