Summary

Name THUMPD3
Full Name tRNA (guanine(6)-N(2))-methyltransferase THUMP3
Synonyms THUMP domain-containing protein 3, tRNA(Trp) (guanine(7)-N(2))-methyltransferase THUMP3, 2.1.1.- |
Primary ID Q9BV44
Links - -
Type protein
Relations 1
Function Catalytic subunit of the THUMPD3-TRM112 methyltransferase complex, that specifically mediates the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotide at position 6 (m2G6) in tRNAs (PubMed:34669960, PubMed:37283053). This is one of the major tRNA (guanine-N(2))-methyltransferases (PubMed:37283053). Also catalyzes the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotide at position 7 of tRNA(Trp) (PubMed:34669960).

Viewer

Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding THUMPD3-TRM112 methyltransferase complex 0.352
Publications: 1 Organism: Homo Sapiens