Summary

Name SF3B5
Full Name Splicing factor 3B subunit 5
Synonyms SF3b5, Pre-mRNA-splicing factor SF3b 10 kDa subunit | SF3B10
Primary ID Q9BWJ5
Links - -
Type protein
Relations 2
Function Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome (PubMed:27720643, PubMed:28781166). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding SF3b 0.928
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding U2 snRNP complex 0.757
Publications: 1 Organism: Homo Sapiens