Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-269662 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
31885126 |
We performed these assays in HEK 293T cells and observed CEP41 binds HIF1α under both normoxic and hypoxic conditions. Of note, we found hypoxia induces more expression of HIF1α and increases its binding to CEP41 (Fig 8B and C). Hence, these results suggest CEP41 modulates the activation of HIF1α via a physical interaction |
|