Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-272845 |
|
|
Homo sapiens |
HCT-116 Cell |
pmid |
sentence |
24980433 |
MDM2 mediates nonproteolytic polyubiquitylation of the DEAD-Box RNA helicase DDX24. Unexpectedly, however, the polyubiquitylation of DDX24 did not elicit its proteasomal degradation but rather promoted its association with preribosomal ribonucleoprotein (pre-rRNP) processing complexes that are required for the early steps of pre-rRNA processing. |
|