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Summary
| Name |  IQCG
|
| Full Name | Dynein regulatory complex protein 9 |
| Synonyms | IQ domain-containing protein G | DRC9 |
| Primary ID | Q9H095 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades. Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | IQCG | form complex 
binding
|
Nexin-dynein regulatory complex | |
| Publications: | 1 | Organism: | Homo Sapiens | |