| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261045 |
|
|
Chlorocebus aethiops |
COS-1 Cell |
| pmid |
sentence |
| 12356756 |
BAP, a Mammalian BiP-associated Protein, Is a Nucleotide Exchange Factor That Regulates the ATPase Activity of BiP. In addition,BAP was associated with BiP in mammalian cells and inter-acted with BiP functionallyin vitro. BAP stimulated the ATPase activity of BiP when added alone or together with the ER DnaJ protein, ERdj4, by promoting the release of ADP from BiP. Together, these data demonstrate that BAP serves as a nucleotide exchange factor for BiP and provide insights into the mechanisms that control protein folding in the mammalian ER. |
|
3.0
SIL1
- 
- 
binding