Summary

Name VPS33B
Full Name Vacuolar protein sorting-associated protein 33B
Synonyms hVPS33B |
Primary ID Q9H267
Links - -
Type protein
Relations 1
Function May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages (PubMed:18474358). Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes (By similarity).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding CHEVI complex 0.789
Publications: 1 Organism: Homo Sapiens