3.0
Summary
| Name |  VPS33B
|
| Full Name | Vacuolar protein sorting-associated protein 33B |
| Synonyms | hVPS33B | |
| Primary ID | Q9H267 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages (PubMed:18474358). Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes (By similarity). |
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binding
dephosphorylation