Summary

Name NELFA
Full Name Negative elongation factor A
Synonyms NELF-A, Wolf-Hirschhorn syndrome candidate 2 protein | WHSC2
Primary ID Q9H3P2
Links - -
Type protein
Relations 1
Function Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding NELF 0.882
Publications: 1 Organism: Homo Sapiens