3.0
Summary
| Name |  ILRUN
|
| Full Name | Protein ILRUN |
| Synonyms | CF106_HUMAN | |
| Primary ID | Q9H6K1 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF (PubMed:29802199). Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP (PubMed:29802199). |
ubiquitination