Summary

Name PLEKHF2
Full Name Pleckstrin homology domain-containing family F member 2
Synonyms PH domain-containing family F member 2, Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains, EAPF, PH and FYVE domain-containing protein 2, Phafin-2, Phafin2, Zinc finger FYVE domain-containing protein 18 | ZFYVE18
Primary ID Q9H8W4
Links - -
Type protein
Relations 1
Function May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis (PubMed:18288467).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding EEA1 0.251
Publications: 1 Organism: In Vitro