Summary

Name VIPAS39
Full Name Spermatogenesis-defective protein 39 homolog
Synonyms hSPE-39, VPS33B-interacting protein in apical-basolateral polarity regulator, VPS33B-interacting protein in polarity and apical restriction | C14orf133, SPE39, VIPAR
Primary ID Q9H9C1
Links - -
Type protein
Relations 1
Function Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753). May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be independent of VPS33B (PubMed:19109425). May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indirect transcriptional regulation of E-cadherin (By similarity).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding CHEVI complex 0.788
Publications: 1 Organism: Homo Sapiens