Name
|
VIPAS39
|
Full Name |
Spermatogenesis-defective protein 39 homolog |
Synonyms |
hSPE-39, VPS33B-interacting protein in apical-basolateral polarity regulator, VPS33B-interacting protein in polarity and apical restriction | C14orf133, SPE39, VIPAR |
Primary ID |
Q9H9C1 |
Links |
- - ![](img/mentha_scaled.png) |
Type |
protein |
Relations |
1 |
Function |
Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753). May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be independent of VPS33B (PubMed:19109425). May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indirect transcriptional regulation of E-cadherin (By similarity). |