3.0
Summary
| Name |  POLR1B
|
| Full Name | DNA-directed RNA polymerase I subunit RPA2 |
| Synonyms | RNA polymerase I subunit 2, DNA-directed RNA polymerase I 135 kDa polypeptide, RPA135 | |
| Primary ID | Q9H9Y6 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | POLR1B | form complex 
binding
|
RNA Polymerase I | 0.866 |
| Publications: | 1 | |||