| Name
|
 MEAF6
|
| Full Name |
Chromatin modification-related protein MEAF6 |
| Synonyms |
MYST/Esa1-associated factor 6, Esa1-associated factor 6 homolog, Protein EAF6 homolog, hEAF6, Sarcoma antigen NY-SAR-91 | C1orf149, CENP-28, EAF6 |
| Primary ID |
Q9HAF1 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
1 |
| Function |
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A (PubMed:14966270). This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription (PubMed:14966270). Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4 (PubMed:16387653, PubMed:24065767). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (PubMed:18794358). |
4.0
binding