3.0
Summary
| Name |  BRF2
|
| Full Name | Transcription factor IIIB 50 kDa subunit |
| Synonyms | TFIIIB50, hTFIIIB50, B-related factor 2, BRF-2, hBRFU | BRFU |
| Primary ID | Q9HAW0 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites (PubMed:11040218, PubMed:11121026, PubMed:11564744, PubMed:26638071). Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress (PubMed:26638071). Down-regulates expression of target genes in response to oxidative stress (PubMed:26638071). Overexpression protects cells against apoptosis in response to oxidative stress (PubMed:26638071). |
binding