Summary

Name PARVB
Full Name Beta-parvin
Synonyms Affixin |
Primary ID Q9HBI1
Links - -
Type protein
Relations 1
Function Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation PARVB
Publications: 1 Organism: Homo Sapiens