Summary

Name ATP13A1
Full Name Endoplasmic reticulum transmembrane helix translocase
Synonyms AT131_HUMAN | ATP13A, KIAA1825
Primary ID Q9HD20
Links - -
Type protein
Relations 2
Function Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum (PubMed:32973005). Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane (PubMed:32973005). Specifically binds mitochondrial tail-anchored transmembrane proteins

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Relations

Regulator Mechanism target score
+ down-regulates img/indirect_inhibition.png Apoptosis 0.7
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png Proliferation 0.7
Publications: 1 Organism: Homo Sapiens