4.0
Summary
| Name |  ARFGAP3
|
| Full Name | ADP-ribosylation factor GTPase-activating protein 3 |
| Synonyms | ARF GAP 3 | ARFGAP1 |
| Primary ID | Q9NP61 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Inhibitors | (2S)-2-[[2-(2,3-dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]-6-purinyl]amino]-3-phenyl-1-propanol |
| Function | GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | (2S)-2-[[2-(2,3-dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]-6-purinyl]amino]-3-phenyl-1-propanol | down-regulates activity 
chemical inhibition
|
ARFGAP3 | 0.8 |
| Publications: | 1 | Organism: | In Vitro | |