3.0
Summary
| Name |  IL26
|
| Full Name | Interleukin-26 |
| Synonyms | IL-26, Protein AK155 | AK155 |
| Primary ID | Q9NPH9 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. |
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