Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-263242 |
|
|
Homo sapiens |
HeLa Cell |
pmid |
sentence |
17396147 |
This complex includes not only the five known FA proteins (FANC‐A, C, E, F, and G), but also four new polypeptides, which are named FAAPs for FANCA‐associated polypeptides. |Thus, eight of the nine components of the FA core complex are FA proteins (FANC‐A, B, C, E, F, G, L, and M). Furthermore, two of the newly discovered FA proteins have enzymatic activities: FANCL is a ubiquitin ligase essential for FANCD2 monoubiquitination in vivo |
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