4.0
Summary
| Name |  A1CF
|
| Full Name | APOBEC1 complementation factor |
| Synonyms | APOBEC1-stimulating protein | ACF, ASP |
| Primary ID | Q9NQ94 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | A1CF | form complex 
binding
|
C-to-U editosome complex | |
| Publications: | 1 | Organism: | Homo Sapiens | |