Summary

Name AGPAT4
Full Name 1-acyl-sn-glycerol-3-phosphate acyltransferase delta
Synonyms 1-acylglycerol-3-phosphate O-acyltransferase 4, 1-AGP acyltransferase 4, 1-AGPAT 4, Lysophosphatidic acid acyltransferase delta, LPAAT-delta |
Primary ID Q9NRZ5
Links - -
Type protein
Relations 2
Function Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png chemical modification phosphatidic acid 0.8
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity img/direct_inhibition.png chemical modification 1-acyl-sn-glycerol 3-phosphate(2-) 0.8
Publications: 1 Organism: Homo Sapiens