Relation Results

Summary

Name ANAPC11
Full Name Anaphase-promoting complex subunit 11
Synonyms APC11, Cyclosome subunit 11, Hepatocellular carcinoma-associated RING finger protein |
Primary ID Q9NYG5
Links - -
Type protein
Relations 2
Function Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulat ...
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Type: Score: Layout: SPV 
0.20.862Ub:E2ANAPC11APC-c

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Relations
Regulator
Mechanism
target
score ℹ
+ Ub:E2up-regulates activity img/direct-activation.png ubiquitination ANAPC11 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-271110 Homo sapiens
pmid sentence
The ubiquitination process is mediated sequentially by three classes of enzymes consisting of a Ub-activating enzyme E1, a Ub-conjugating enzyme E2, and a Ub ligase E3. Ub is first activated by E1 in an adenosine 5′-triphosphate (ATP)-dependent manner t
Publications: 1 Organism: Homo Sapiens
+ ANAPC11form complex img/form-complex.png binding APC-c 0.862
Identifier Residue Sequence Organism Cell Line
SIGNOR-252010
pmid sentence
The anaphase promoting complex/cyclosome (APC/C) is a ubiquitin ligase that has essential functions in and outside the eukaryotic cell cycle. It is the most complex molecular machine that is known to catalyse ubiquitylation reactions, and it contains more than a dozen subunits that assemble into a large 1.5-MDa complex.
Publications: 1
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