Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-166417 |
Ser435 |
RSIRRRDsCLNSKTK |
Homo sapiens |
|
pmid |
sentence |
20577264 |
In this study, we show that g2 and s-phase-expressed 1 (gtse1) protein, a negative regulator of p53, is required for g2 checkpoint recovery and that plk1 phosphorylation of gtse1 at ser 435 promotes its nuclear localization, and thus shuttles p53 out of the nucleus to lead to its degradation during the recovery. |
|