Relation Results

Summary

Name NDUFA13
Full Name NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
Synonyms Cell death regulatory protein GRIM-19, Complex I-B16.6, CI-B16.6, Gene associated with retinoic and interferon-induced mortality 19 protein, GRIM-19, Gene associated with retinoic and IFN-induced mortality 19 protein, NADH-ubiquinone oxidoreductase B16.6 subunit | GRIM19
Primary ID Q9P0J0
Links - -
Type protein
Relations 2
Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis (Pu ...
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Type: Score: Layout: SPV 
0.7910.2NDUFA13Mitochondrial respiratory chain complex ITFEB

Relations

Regulator
Mechanism
target
score
+ form complex img/form-complex.png binding Mitochondrial respiratory chain complex I 0.791
Identifier Residue Sequence Organism Cell Line
SIGNOR-262153
pmid sentence
Thus, we now know the complete mammalian cI structure [22,23] and how the subunits are organized in six modules (N, Q, ND1, ND2, ND4 and ND5)|The ND1-module builds around the Q-module with the help of TIMMDC1/C3ORF1 [47,48], which remains bound to the Q/ND1 subassembly until the last maturation steps. MT-ND1 joins first and then NDUFA3, NDUFA8 and NDUFA13 are added
Publications: 1
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation NDUFA13 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-276701
pmid sentence
Genes responsive to high, sustained levels of nuclear TFEB induced by Torin treatment included CTSF, NPC2, BLOC1S3, and BLOC1S2, which function in lysosomal degradation, transport, and biogenesis; NDUFS4, NDUFA13, NDUFA8, NDUFA1, NDUFB10, and NDUFAF2, subunits of mitochondrial NADH dehydrogenase; PPARG and PPARGC1A, a nuclear receptor and co-factor regulating lipid metabolism; and BHLHE40 and BHLHE41, two transcriptional repressors (Figures 4B and 4D; Table S4).
Publications: 1
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